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Cardiovascular Disease is the leading cause of death in patients with rheumatoid arthritis.

Patients with rheumatoid arthritis (RA) are at a higher risk for cardiovascular disease (CVD) because long-lasting inflammation can damage arteries and may cause a buildup of plaque over time.¹ Patients with RA have an approximately 50% greater risk for CVD compared to the general population.²

 

 

30% of cardiovascular (CV) risk in patients with RA is attributed to systemic inflammation and other RA-related factors.³ High RA inflammation levels are associated with serious infections, myocardial infarctions (MI), coronary heart disease, and damage to organs and systems beyond the joints.4 Vectra® is an advanced blood test that can help monitor and measure inflammation in patients with RA.

The Vectra Report now includes a multi-biomarker disease activity-based CV risk assessment. Vectra Cardiovascular Risk can be added to the Vectra test at no additional cost. Vectra Cardiovascular Risk incorporates a personalized assessment of inflammation to predict an RA patient’s risk of a CV event in the next 3 years.5 Vectra Cardiovascular Risk provides an actionable result at point of care that highlights the role of reducing systemic inflammation associated with RA.

Learn how Vectra Cardiovascular Risk can help you manage your patients’ cardiovascular risk associated with their RA inflammation.

Visit Vectra Cardiovascular Risk Homepage

1. Aviña-Zubieta JA, Choi HK, Sadatsafavi M, Etminan M, Esdaile JM, Lacaille D. Risk of cardiovascular mortality in patients with rheumatoid arthritis: a meta-analysis of observational studies. Arthritis Rheum. 2008;59(12):1690-7.
2. Aviña-Zubieta JA, Choi HK, Sadatsafavi M, Etminan M, Esdaile JM, Lacaille D. Risk of cardiovascular mortality in patients with rheumatoid arthritis: a meta-analysis of observational studies. Arthritis Rheum. 2008;59(12):1690-7.
3. Crowson CS, Rollefstad S, Ikdahl E, Kitas GD, van Riel P, Gabriel SE, et al. Impact of risk factors associated with cardiovascular outcomes in patients with rheumatoid arthritis. Ann Rheum Dis. 2018;77(1):48-54.
4. Curtis JR, Xie F, Chen L, Saag KG, Yun H, Muntner P. Biomarker-related risk for myocardial infarction and serious infections in patients with rheumatoid arthritis: a population-based study. Ann Rheum Dis. 2018 Mar;77(3):386-392. doi: 10.1136/annrheumdis-2017-211727. Epub 2017 Dec 21. PMID: 29269418.
5. Curtis, J.R., Xie, F., Crowson, C.S. et al. Derivation and internal validation of a multi-biomarker-based cardiovascular disease risk prediction score for rheumatoid arthritis patients. Arthritis Res Ther 22, 282 (2020). https://doi.org/10.1186/s13075-020-02355-0
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